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Publisher > STM Publishing > Web-based Information services > Reference Tools> Scientific Information - Chemistry / Chemical Sciences
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Thieme announces latest SOS 4.11 release, Science of Synthesis gets content boost
- 09 Aug 2018

Science of Synthesis 4.11, the latest release of Thieme's knowledge base for synthetic methodology, features insights on carbolines and S,S-acetals as well as catalytic reduction. The update consists of a reference library volume as well as a new Knowledge Update, comprising approximately 970 pages of new content.

Available a mere two weeks after publication of the hard copy, Knowledge Update 2018/2 features a major new chapter on carbolines or pyrido[X,Y-b]indoles by J. A. Joule. The chapter covers the synthesis of all four regioisomeric heterocyclic systems found in both natural products and pharmaceuticals. Highlights of this release also include an introductory chapter on S,S-acetals by T.-Y. Luh and M.k. Leung, describing their use as protecting groups for carbonyl compounds and as alternative functional groups for further transformations. Also included are new knowledge-base chapters on the synthesis of 1,3-dithietanes and 1,3-dithiolanes by T.-Y. Luh, M.k. Leung, and C.-M. Chou, as the latter are particularly important as masked carbonyl compounds.

The new Knowledge Update volume comprises a total of approximately 500 printed pages representing the most up-to-date and reliable synthetic methods. SOS Knowledge Updates are governed by clearly defined criteria for method selection as well as established editorial processes. Due in great part to this discerning and continuous updating process, SOS prevails as one of the most up-to-date evaluated electronic reference works available, emphasizing the most significant developments in synthetic methodology.

Following the addition of the first volume with SOS 4.10 in March, SOS 4.11 now expands the Reference Library with Catalytic Reduction in Organic Synthesis, Vol. 2 edited by J. G. de Vries. This volume, like Volume 1, includes the latest developments in the field of catalytic reductions. In addition to covering both heterogeneous and homogeneous catalytic systems, Catalytic Reduction in Organic Synthesis offers a good representation of enantioselective methodology. Comprising 468 printed pages, Volume 2 focuses on carbonyl group reductions, with contributions on the reduction of aldehydes, ketones, and carboxylic acids and derivatives. Also covered are important reductions of specific functional groups including nitriles, azides, and nitro compounds.

With expert evaluated content focusing on subjects of particular current interest, the SOS Reference Library complements the SOS Knowledge Updates to make SOS the complete information source for the modern synthetic chemist.

Brought to you by Scope e-Knowledge Center, a trusted global partner for digital content transformation solutions - Abstracting & Indexing (A&I), Knowledge Modeling (Taxonomies, Thesauri and Ontologies), and Metadata Enrichment & Entity Extraction.

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Thieme releases Science of Synthesis 4.10 with updated user interface
- 06 Apr 2018

Medical and scientific publishing house Thieme Publishing Group has released Science of Synthesis 4.10 that features an updated user interface to make searching and exploring the full-text resource easier than ever. With the addition of an update volume and a reference library volume, this release also includes plenty of exciting new content.

Science of Synthesis (SOS) presents the latest, most significant developments in synthetic methodology, with new peer-reviewed content added on a regular basis. This latest update to Science of Synthesis expands the knowledge base with a new Knowledge Updates volume comprising more than 500 printed pages. J.-M. Weibel, A. Blanc, and P. Pale have contributed a chapter on silver-promoted coupling reactions. Highlights also include an update by A. Ulfkjær and M. Pittelkow on 1‑(organochalcogeno)alkynes that covers the synthesis and applications of sulfur-, selenium-, and tellurium-substituted alkynes, which are of importance as building blocks and intermediates in organic synthesis. In a series of update chapters by C. González-Bello, the modification of phenols as well as their synthesis by substitution, elimination, and rearrangement reactions are reviewed, thereby detailing novel approaches for installing the phenol functionality in natural and synthetic compounds. With an update on arylphosphinic acids and derivatives, D. Virieux et al. cover advances made in the synthesis of this important class of organophosphorus compound over the past decade. A Knowledge Updates chapter by A. S. K. Hashmi on the synthesis of heteroatom-substituted allenes describes methods for the synthesis of the allene functionality as well as the installation of heteroatoms onto a pre-existing allene. Finally, the latest SOS release features a new chapter by V. Hessel et al. on immobilised biocatalysts and their application in flow chemistry, a topic that has attracted intense interest in recent years. The chapter provides practitioners with the insights necessary to combine the outstanding selectivity associated with biocatalysts and the ease of separation as well as further practical advantages of using a heterogeneous catalyst in a flow reactor.

The latest addition to the SOS Reference Library, Catalytic Reduction in Organic Synthesis (Vol. 1), edited by J. G. de Vries, includes the latest developments in the field of catalytic reductions, as well as selective coverage of more well-established methods. The reference work presents both heterogeneous and homogeneous catalytic systems, and also has a strong focus on enantioselective methodology. Covering the hydrogenation of alkenes, polyenes, arenes, hetarenes, alkynes, and allenes, the volume caters to the increasingly important field of converting renewable resources into fuels and chemicals, which often relies on deoxygenation through hydrogenation or hydrogenolysis as an important first step in the conversion of biomass. Additional topics include alcohol reduction, ether hydrogenolysis, and the reduction of carbonates and carbon dioxide.

Responding to the needs and priorities of the user, the starting point in SOS 4.10 has been changed to the Query tab, with text and structure/reaction search functionalities now immediately at the user's fingertips. To further improve navigation and content search, the Explore Contents tab now includes graphical/text abstracts for the Knowledge Updates and Reference Library content. The most striking visual change of the latest SOS release is the implementation of Thieme's blue-blue-white corporate colors.

The updating process for Science of Synthesis is guided by strict criteria to ensure that only the best and most reliable synthetic methods are included. The Editorial Board, in conjunction with the volume editors and authors, review the whole field of synthetic organic chemistry as presented in SOS and evaluate significant developments in synthetic methodology.

Brought to you by Scope e-Knowledge Center, a trusted global partner for digital content transformation solutions - Abstracting & Indexing (A&I), Knowledge Modeling (Taxonomies, Thesauri and Ontologies), and Metadata Enrichment & Entity Extraction.

Thieme releases Science of Synthesis 4.8 with Name-to-Structure Functionality and 1,000 Pages of New Content
- 24 Jul 2017

Medical and scientific publishing house Thieme Publishing Group has released Science of Synthesis 4.8 with Name-to-Structure Functionality and 1,000 Pages of New Content.

With its latest release of the unique full-text resource Science of Syntheses (SOS), Thieme introduces a name-to-structure functionality that allows users to generate chemical structures from names. In addition to a new 'Hit Select/Deselect' option, SOS 4.8 also includes two new update volumes comprising approximately 1,000 printed pages.

Combining a dictionary-based and an algorithmic approach, the name-to-structure functionality generates chemical structures from their names. Users merely need to type in the name of the chemical and the new functionality delivers the corresponding structure. The name-to-structure tool uses InfoChem's comprehensive dictionary of over 28 million chemical names corresponding to more than 13 million unique structures. While the majority of the names in the dictionary are in English and German, it also includes the names of common chemicals in a variety of other languages. The new functionality offers users great flexibility, as it can process names based on systematic nomenclature as well as trade, trivial, and semi-systematic names.

The latest release of Science of Synthesis includes two new Knowledge Update volumes representing approximately 1,000 printed pages. Full-text and structure/reaction searching, as well as downloadable chapter PDFs, is available for all content. The updating process for Science of Synthesis is guided by strict criteria to ensure that only the best and most reliable synthetic methods are included. New content will continually be added to the digital version, which prevails as the most up-to-date evaluated digital reference work available, reflecting the latest developments in synthetic methodology.

To improve the processing of generated hit lists, SOS 4.8 offers a range of options for selecting and deselecting hits. This allows users to refine their hit lists more conveniently and represents yet another user-friendly feature of the resource.

Brought to you by Scope e-Knowledge Center, a world-leading provider of Abstracting & Indexing (A&I) Services, Knowledge Modeling Services (Taxonomies, Thesauri and Ontologies), Metadata Enrichment & Entity Extraction Services.

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Thieme Chemistry releases Science of Synthesis 4.5, includes Metal-Catalysed Cyclisation Reactions and latest updates
- 05 Oct 2016

Scientific publisher Thieme Chemistry has released the latest update of its most up-to-date evaluated digital reference work, Science of Synthesis, adding two new volumes on metal-catalysed cyclisation reactions. Science of Synthesis 4.5 comprises a total of more than 1,800 printed pages of new content, including a series of important knowledge updates.

Among the highlights of the latest Science of Synthesis release 4.5 are over 1,300 pages on Metal-Catalysed Cyclisation Reactions, edited by Shengming Ma from the Shanghai Institute of Organic Chemistry, China and Shuanhu Gao from the East China Normal University in Shanghai, China and compiled by 36 authors worldwide. Significant advances in metal-catalysed reactions, especially cyclisations, have dramatically improved the efficiency of organic synthesis over the last three decades. To date, the transformations are widely used in the area of synthesis of both natural products and therapeutic agents. 'Science of Synthesis: Metal-Catalysed Cyclisation Reactions' presents the most commonly used and significant metal-catalysed reactions for modern organic synthesis in two volumes. Volume 1 covers intramolecular allylations, intramolecular coupling reactions including Heck reactions, as well as cyclopropane and cyclopropene ring openings. Also included are cyclisation reactions of alkenes, alkynes, and allenes, cycloisomerisations, and intramolecular C—N and C—O bond formation. Volume 2 covers epoxidations, aziridinations, cyclopropanations, and Pauson–Khand reactions, as well as a wide range of cycloaddition processes, radical cyclisations, and ring-closing metathesis.

In addition to the two new reference volumes, the latest knowledge update volume comprises a total of 500 printed pages, including a major contribution by D. Spitzner on the synthesis of pyridines, pyridinium salts, and pyridine N-oxides.

Science of Synthesis continues to be updated following established editorial processes with clearly defined criteria and discerning standards for method selection. New content will continually be added to the digital version, which prevails as one of the most up-to-date evaluated digital reference works available, reflecting the latest developments in synthetic methodology. All content is available with full text and graphics and can be searched by structure and reaction type.

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Thieme Chemistry releases Science of Synthesis 4.4, includes Domino Transformations and latest updates
- 18 Jul 2016

Thieme Chemistry has released version 4.4 of its unique full-text resource Science of Synthesis (SOS). With the release of Science of Synthesis 4.4, Thieme Chemistry seeks to expand its definitive knowledge base to include significant knowledge updates as well as two new reference library volumes on domino transformations in organic synthesis.

The latest addition to the Science of Synthesis reference library, Applications of Domino Transformations in Organic Synthesis (Vols. 1 and 2), edited by Scott A. Snyder, highlights the current state of the art in the rapidly changing field of domino/cascade-based transformations. The two volumes are organised by the core type of reaction used to initiate the domino event. Volume 1 covers polyene/cation-π cyclizations, the synthesis of polyether natural products by polyepoxide ring-opening, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements. Volume 2 focuses on pericyclic reactions, for example sigmatropic shifts and ene reactions. Alkylative dearomatization reactions, additions to non-activated alkenes (e.g., halocyclizations), activated alkenes (e.g., Michael reactions, enamine/enol ether reactions), and to C=O and C=N bonds are also covered in this volume.

To ensure that the unique synthetic methodology tool continues to offer the most current and reliable information on chemical transformations, Science of Synthesis 4.4 includes knowledge updates comprising a total of 500 printed pages. Among the highlights of the latest knowledge update are new insights on the synthesis and applications of organometallic complexes of platinum and on the applications of organometallic complexes of iridium. A significant update on the synthesis of 1,2,3-triazoles focuses on the addition of azides to alkynes and alkenes in "click chemistry", which has received much interest over the past few years.

Furthermore, the recently expanded knowledge base includes updates on the synthesis of phthalazines and quinazolines. Both nitrogen heterocycle classes have been a recent focus of attention from the pharmaceutical industry. Highlights of the current update also include updates on the syntheses of various non-aromatic phosphorus-containing heterocycles, oxygen- and phosphorus-substituted alkynes, and nitrogen-substituted alkynes. The update on nitrosoalkenes covers new methods for the synthesis of these generally unstable compounds along with their applications, particularly in cycloadditions and 1,4-additions. A series of updates on the synthesis of haloalkanes rounds off the latest knowledge updates, covering synthesis by substitution of hydrogen atoms, metals or carbon functionalities, and other halogens or oxygen functionalities, as well as by addition across carbon-carbon multiple bonds. Contributors to the latest SoS Knowledge Update include A. Nomoto and A. Ogawa; H. Li and C. Mazet; A. C. Tomé; T. J. Hagen and T. R. Helgren; F.-A. Kang and S.-M. Yang; M. H. Larsen, M. Cacciarini, and M. Brøndsted Nielsen; K. Banert; H.-U. Reissig and R. Zimmer; G. Keglevich and A. Grün; J. Iskra and S. S. Murphree; M. C. Elliott and B. A. Saleh; F. V. Singh and T. Wirth; and U. Hennecke.

Science of Synthesis continues to be updated following established editorial processes with clearly defined criteria and discerning standards for method selection. New content will continually be added to the digital version, which prevails as the most up-to-date evaluated digital reference work available, reflecting the latest developments in synthetic methodology. All content is available with full text and graphics and can be searched by structure and reaction type.

To access Science of Synthesis 4.4 or get a free trial please visit: http://sos.thieme.com.

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Thieme Chemistry releases version 4.3 of unique full-text resource Science of Synthesis
- 22 Mar 2016

Thieme Chemistry has released version 4.3 of its unique full-text resource Science of Synthesis (SOS). Available as of March 2016, this update will see the addition of one new Knowledge Update with approximately 500 printed pages as well as two new reference library volumes comprising a total of 1,042 printed pages.

The latest release of Science of Synthesis will see the addition of SOS Knowledge Updates comprising approximately 500 printed pages. In addition to a major update on the synthesis of vinylsilanes and silyl hydrides, highlights of this release include updates on important compounds used in cross-coupling chemistry, such as fluoroarenes, chloroarenes and bromoarenes. The update on the chemistry of hypervalent iodoarenes and iodonium salts contains significant new developments such as their in situ generation and use in catalytic reactions, recyclable reagents, and the synthesis and application of chiral hypervalent reagents. The extensive update on arylphosphine oxides and heteroatom derivatives presents various new methods for the synthesis of arylphosphine oxides.

The updating process is guided by strict criteria to ensure that only the best and most reliable synthetic methods are included in SOS. Among the renowned specialists who added to this latest release are experts including R. W. Clark and S. L. Wiskur, E. A. Anderson and D. S. W. Lim and A. Harsanyi and G. Sandford, to name a few. All of them have expanded the knowledge base with new methods as well as new or completely revised product (sub-) classes. New content will continually be added to the digital version, which prevails as the most up-to-date evaluated digital reference work available, reflecting the latest developments in synthetic methodology.

The Science of Synthesis Reference Library has also been expanded to include two new volumes comprising a total of 1,042 printed pages: Catalytic Transformations via C—H Activation, Vols. 1 and 2, edited by Prof. Jin-Quan Yu and with contributions from over 40 expert authors. Volume 1 focuses on the formation of C—C bonds by both arene and hetarene C—H activation, while Volume 2 examines the formation of C—C bonds by C—H activation of non-(het)arene substrates as well as C—H activation using special reagents or techniques. Both volumes contain articles by experts in the field presenting the best synthetic methods, including typical or general experimental procedures. Thus, this latest SOS Reference Library addition can serve as both a basis for the practical application of the techniques discussed and as a foundation for future research.

To gain access to Science of Synthesis 4.3 or for a free trial interested parties may visit http://sos.thieme.com.

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Thieme Chemistry releases Science of Synthesis 4.1
- 30 Jun 2015

Scientific publisher Thieme Chemistry has announced Science of Synthesis (SOS) 4.1, the latest release of its unique full-text resource for methods and experimental procedures in synthetic organic chemistry. Available as of June, Science of Synthesis will include the latest Knowledge Updates and additions from the Reference Library – a total of approximately 1,650 printed pages of new material. An enhanced interface design and increased content linking through Digital Object Identifiers further enrich the user experience.

The latest release of Science of Synthesis will see the addition of SOS Knowledge Updates comprising approximately 500 printed pages. It includes an entirely new chapter on five-five-fused hetarenes featuring examples of more unusual selenium and tellurium systems. The use of supercritical carbon dioxide as a reaction medium for organic synthesis is another focus. These are only the latest in a continuous series of knowledge updates that follow proven editorial processes and strict criteria for method selection to ensure consistently high content quality. New content will frequently be added to the digital version, which continues to be the most up-to-date evaluated digital reference work available, reflecting the latest developments in synthetic methodology.

The available content from the Science of Synthesis Reference Library has also been expanded to include two new volumes comprising a total of 1,168 printed pages. C-1 Building Blocks in Organic Synthesis (2 vols.), edited by Piet W. N. M. van Leeuwen and written by 54 experts, reviews a wide range of reactions to form C–C bonds, including reactions involving catalytic methods, an area that has seen significant developments in recent years. The authoritative overview includes contributions on the first catalysts to enable the introduction of fluoromethyl groups in aromatics.

Science of Synthesis 4.1 also comes with an enhanced interface design that features book covers with zoom functionality to facilitate navigation and allow for a quick overview of volume editors. The linking to the primary literature through Digital Object Identifiers is increased to further enrich the user experience. The latest SOS version also includes a number of bug fixes and general software improvements to ensure smooth and stable product performance. Many of the suggested fixes arose after intensive discussions with the customer base worldwide (through WebEx sessions, company visits and international roadshows).

Interested parties may visit http://sos.thieme.com to get access to Science of Synthesis 4.1 or a free trial.

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Thieme Chemistry releases Science of Synthesis 4.0.1
- 07 Oct 2014

Thieme Chemistry, Germany, has announced the release of Science of Synthesis 4.0.1 - the only full-text resource for methods and experimental procedures in synthetic organic chemistry. The new version, available as of October 6th, 2014, offers a range of new features as well as 13 new content volumes covering topics such as Cross Coupling and Heck-Type Reactions and Multicomponent Reactions. New features include improved text-search capabilities and a new non-Java chemical structure editor.

Eight of the thirteen new volumes on SOS are Science of Synthesis Knowledge Update volumes dating from 2012 to 2014. Highlights include a comprehensive review of asymmetric transformations catalysed by gold salts published between 2005 and 2011 by M. J. Campbell and F. D. Toste; a new chapter outlining many of the methods used to synthesize α-aryl ketones and α-hetaryl ketones by J. C. Collings; and an entirely new chapter on thioaldehyde and thioketone S-sulfides (thiosulfines) overviewing methods for their in situ generation as well as their application by G. Mlostoń and H. Heimgartner.

The other five volumes comprise part of the much-acclaimed Science of Synthesis Reference Library series. Cross Coupling and Heck-Type Reactions consists of three volumes written by 96 experts and edited by G. A. Molander, J. P. Wolfe and M. Larhed. It includes the best methods currently available for the formation of new carbon - heteroatom and carbon- carbon bonds using metal-catalysed cross-coupling reactions. The two volumes Multicomponent Reactions written by 63 leading chemists in the multicomponent reactions field and edited by T. J. J. Müller critically review the state of the art of domino, sequential, and consecutive multicomponent reactions.

With the new HTML5 structure editor, which is very easy and intuitive to use, users can draw chemical structures within their Web browser without the need for plugins like Java. This then eliminates the need to adjust security settings or gain additional administration rights for Java issues as has been the case in the past.

An improved search function enables users to find specific Science of Synthesis articles quickly using additional operators in the text search box.

Science of Synthesis provides a critical review of the synthetic methodology developed to date in the fields of organic and organometallic chemistry. The content is compiled and updated by a community of over 1,750 renowned chemists worldwide.

To get access to the product or a free trial, interested parties may visit - http://sos.thieme.com.

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New interface, powerful search functionalities and personalisation options increase usability of Science of Synthesis version 4.0
- 12 Mar 2014

Medical and scientific publisher Thieme has added a number of new features to its acclaimed critical review of synthetic methodology with the latest release 4.0 of Science of Synthesis (SOS). This includes the Reference Library, enriched search functionalities, a new, user-friendly interface, as well as customisation options.

The Reference Library, a new addition in release 4.0, is edited by outstanding organic chemists worldwide who have selected the best and most reliable methods in their respective fields. Designed to complement the volumes of Science of Synthesis, the Reference Library highlights new approaches and perspectives of particular current interest in organic synthesis. SOS 4.0 now includes all volumes of "Stereoselective Synthesis", "Asymmetric Organocatalysis" and "Water in Organic Synthesis".

Furthermore, the latest release of SOS sees the addition of 10 new update volumes comprising approximately 5,000 printed pages. As the most up-to-date evaluated electronic reference work available, Science of Synthesis is continually updated to include only high-quality, highly reliable methods. Each volume is edited by experts of the respective fields who follow strict, clearly defined criteria for method selection and continually scan current literature for relevant new developments. This established editorial process ensures that SOS always reflects the current state of knowledge.

To allow users to efficiently mine this wealth of content, Thieme has implemented enriched text search functionalities based on the MarkLogic platform, allowing users to perform real-time text searches. Search options are further enhanced by the new RSA search from InfoChem, an "all-in-one" reaction search operator that combines reaction, exact, and substructure searches for each single search query, listing the results according to relevance. Both text searches and reaction searches are performed via the same search screen into which users simply enter a keyword, structure or reaction. Within seconds, relevant results are found, evaluated, and displayed in an interactive hit list, where users can explore them via multiple filters. All search queries and results can then be saved in the new, personalized user profile MySOS, which offers easy access to relevant content and previous searches.

In addition to new content and search features, users can look forward to navigation options that increase the usability of the online offer. A new breadcrumb trail ensures easy navigation, while a detailed and interactive table of content can be accessed via the added "Explore Content" tab. Users are thus able to browse the entire content quickly and efficiently. Further features of the latest SOS release include PDF download and enhanced print options for printing individual pages and chapters. Inbound and outbound DOIs (digital object identifiers) allow links from and to external sources for easy identification and citation of individual SOS chapters.

Science of Synthesis, a research tool by Thieme, claims to be the only resource for methods in synthetic organic chemistry that offers full-text descriptions of organic transformations and synthetic methods, as well as experimental procedures. The inclusion of effective and practical experimental procedures means that the chemist can get to work on a synthesis immediately in the lab. Science of Synthesis provides a critical review of the synthetic methodology in the field of organic and organometallic chemistry.

Knovel introduces Specialty Chemicals Essentials
- 16 Nov 2010

Knovel, a Web-based application integrating technical information with analytical and search tools, has announced the immediate availability of the Specialty Chemicals Essentials package. The package offers guidance and best practice information to support efficient, faster and safer processing, production and development of specialty chemicals.

Knovel offers validated reference data sourced from over 70 recognised societies and publishing partners. Specialty Chemicals Essentials enables engineers to jumpstart their use of Knovel with access to content that many top firms frequently use, including seven of the top 10 US specialty chemical companies.

Strategically selected from the 24 total subject areas Knovel offers, the Specialty Chemicals Essentials package includes content and data analysis tools in five subject areas. These are: Chemistry & Chemical Engineering; General Engineering & Engineering Management; Mechanics & Mechanical Engineering; Safety, Health & Hygiene; and Plastics & Rubber.

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Thieme releases latest version of online chemistry resource Science of Synthesis
- 21 Sep 2010

STM publisher Thieme Publishing Group, Germany, has announced the release of Science of Synthesis 3.10, an online resource providing users with access to chemical information from experts in the field.

With the latest upgrade, Science of Synthesis claims to cover all fields of organic chemistry from organometallics to alkanes. Covered topics will be continuously updated and additional content will be added to the electronic reference through multiple releases per year. The latest release encompasses 14,452 new reactions, with over 68,000 structures. Detailed preparative expertise is provided on: nitro, nitroso, azo, azoxy, and diazonium compounds, azides, triazenes, and tetrazenes (Volume 41); alkenes (Volume 47); and alkanes (Volume 48).

Developed in cooperation with InfoChem, Science of Synthesis seeks to present a critical treatment of synthetic organic chemistry from the early 1800s to the present. As a first point of reference for the synthetic chemist, the resource is projected to possess a user-friendly search function that allows substructure, exact structure, reaction, combined keyword, and full-text searches. Within the application, a structure search is supposedly quick and easy since users have the ability to choose between multiple structure drawing tools (ISIS Draw, Java Applet and ChemDraw). Its compatibility with SFX is seen to assist librarians in navigating literature requests of Science of Synthesis users to resources and services relevant to their search queries.

Science of Synthesis Version 3.10 is fully compatible with both Windows and Macintosh and supports Internet Explorer, Firefox and Safari browsers.

From 2010 onwards the existing volumes in the resource will be complemented by a variety of organic synthesis specialist topic reference works. A modular approach will be used to build the Science of Synthesis Reference Library, developed in conjunction with members of the Science of Synthesis Editorial Board.

To access our daily STM news feed through your iPhone, iPad, or other smartphones, please visit www.myscoope.com for a mobile friendly reading experience.


ACS and Council for Chemical Research to host R&D symposium
- 13 Aug 2010

The American Chemical Society (ACS) and the Council for Chemical Research (CCR) will hold a special half-day symposium to address the critical challenge of keeping the US' chemical enterprise competitive, and the central role research and development (R&D) will play in this process.

Entitled 'Translational Chemical R&D: The Driving Force for Job Creation', the event is scheduled for August 22, during the ACS National Meeting & Exposition. The symposium will take place in Room 210A of the Boston Convention and Exhibition Center, and will include experts from the chemical enterprise. A private reception for further discussion with the speakers and other R&D leaders will follow the event.

The symposium will be divided into two sessions. In the first, presenters will explore big picture trends and new tools to maximise the impact of R&D. In the second session, presenters will focus on tools to translate R&D to commercialisation, such as open collaboration, venture investment in spin-offs, and R&D centers or hubs.

More than 8,000 reports on new advances in medicine, health, energy, environment, and other scientific disciplines that involve chemistry will be presented during the ACS National Meeting.

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Royal Society of Chemistry announces start of new global conference series
- 29 Jul 2010

The Royal Society of Chemistry (RSC) has announced that well-known scientists in the chemical sciences field appeared at the RSC's three conferences in three continents for the launch of the new flagship journal, Chemical Science. These conferences were held over three successive weeks in July.

Commencing in San Francisco earlier this month, the inaugural meetings heralded the start of a new global conference series, aligned to the new journal. The International Symposia on Advancing the Chemical Sciences (ISACS) events are an integral part of the RSC's mission to advance the chemical sciences.

In opening the first event, Dr James Milne, editorial director of the RSC, explained how hosting three conferences in three different continents represents the international nature for the conference series, the new journal Chemical Science, and the RSC as a society. This vision was endorsed by the journal's editor-in-chief, David MacMillan, from Princeton University.

Each meeting, held over four days, contained 18 plenary lectures given of the world's leading researchers in their respective fields. The RSC also welcomed close to 200 new members who joined the society as a result of the conferences. The first issue of Chemical Science was published just a few weeks before the first meeting, and received significant praise from delegates and speakers. Many confirmed plans to submit their latest research results to the journal, which aims to surpass the standards set by other leading general chemistry titles.

Plans are already underway for next year's three ISACS meetings, which will be spread throughout the summer of 2011. Many delegates have already registered an interest in attending future ISACS meetings, suggesting this will quickly become an established and exceptional series for the chemical science research community.

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Carnegie Mellon's ChemCollective website receives science prize for online resources in education
- 30 Apr 2010

Carnegie Mellon University has announced that its ChemCollective website has received the Science Prize for Online Resources in Education (SPORE). The award, sponsored by Science magazine, recognises outstanding freely available online materials that enrich science education.

The ChemCollective website (www.chemcollective.org), developed by researchers at Carnegie Mellon University, seeks to provide chemistry instructors with access to virtual lab and scenario-based learning activities. It gives introductory level chemistry students the opportunity to participate in activities that go beyond traditional textbook problems, allowing them to engage with chemistry in a way that more closely resembles the activities of practicing chemists.

Associate Professor of Chemistry David Yaron and his team, made up of software engineers, undergraduate programmers and educational consultants, began developing the resources used in the ChemCollective in 2000, and the site was launched in its current format in 2004. Last year, more than 100,000 experiments were performed on the website and the software was downloaded more than 25,000 times for use on local computers. Many instructors have submitted their own materials to the site to be shared among users. Of the 117 labs currently available on the site, 56 have been contributed by 11 different groups from the user community.

Science magazine announces one recipient of the SPORE award each month throughout the year, publishing an essay on each programme. The essay on the ChemCollective appears in the April 30 issue. Co-authors of the essay include Carnegie Mellon's David Yaron, Michael Karabinos and alumnus Donovan Lange, along with James G. Greeno and Gaea Leinhardt from the University of Pittsburgh.

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Wiley, Reaction Explorer partnership to offer interactive organic chemistry learning system with textbooks
- 16 Apr 2010

Publisher John Wiley & Sons, Inc., US, has announced a partnership with Reaction Explorer to bring new capabilities to the online organic chemistry market.

Students can access Reaction Explorer through WileyPLUS, an online teaching and learning solution for organic chemistry. Reaction Explorer is projected to help students achieve a higher level of understanding of the intricacies of organic chemistry reactions, syntheses and mechanisms.

Reaction Explorer was initially developed at the University of California, Irvine, in the laboratory of Professor Pierre Baldi, and has been used there for over 3 years to teach undergraduate organic chemistry. It uses expert system technology to predict the results of arbitrary organic chemistry reactions. This unique ability allows students to explore the results of novel reactions, regardless of whether they were anticipated by the developers.

The Reaction Explorer system has two primary modules, focusing on the most challenging and important problem-solving skills students learn in organic chemistry. Synthesis Explorer allows students to interactively learn and work through multi-step retrosynthesis problems, while Mechanism Explorer challenges a student’s ability to propose and sketch reasonable organic reaction mechanisms.

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Thieme Publishing Group launches Version 3.9 of Science of Synthesis resource
- 31 Mar 2010

STM publisher Thieme Publishing Group, Germany, has announced the launch of Science of Synthesis Version 3.9, an online resource that provides highly evaluated chemical information from leading experts in the field. This critical treatment of synthetic chemistry claims to be one of the most authoritative, in-depth information resources available on synthetic methodology. It contains comprehensive coverage of the entire field of organic chemistry from all published and readily available sources from the early 1800s until the present.

With this upgraded version, 45 out of the 48 printed volumes are now available online. Over 14,000 new reactions and an additional 1,545 experimental procedures have been added to this release. There are currently a total of 252,000 reactions and more than 32,000 experimental procedures available.

Developed in cooperation with InfoChem, Science of Synthesis possesses a user-friendly search function that allows substructure, exact structure, reaction, combined keyword, and full-text searches. Within the application, a structure search is quick and easy since users have the ability to choose between multiple structure drawing tools (ISIS Draw, Java Applet, and ChemDraw). Its compatibility with SFX assists librarians in navigating literature requests of Science of Synthesis users to resources and services relevant to their search queries.

Science of Synthesis Version 3.9 is fully compatible with both Windows and Macintosh and supports Internet Explorer, Firefox, and Safari browsers.

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