Thomson Reuters, a US-based provider of information for businesses and professionals, has announced the addition of Prous Science routes of synthesis (ROS) data to the Newport Horizon Premium and Newport Vision Premium solutions. An ROS focused search allows users to identify active pharmaceutical ingredients (APIs) according to an intermediate or reagent used, number of available routes or by patents referenced in a given route.
Provided free of charge to current subscribers of the Premium systems, this new dataset, compliments the kilogram demand data released in March. Also, it enhances product targeting, business development and competitive intelligence by helping users to understand better the chemistry and manufacture of APIs.
The true or original manufacturing process used for a particular API is usually well protected by patents, making it challenging to devise equivalent, cheaper or more efficient processes without infringing on the originator's intellectual property. The new dataset will help to remedy this by providing extensive information for more than 2,500 APIs, consisting of full chemical name; CAS number; synthesis route diagram text commentary (with each step indexed to the diagram); patent references (linked to the patent page); intermediate chemicals and CAS numbers; reagent chemicals and CAS numbers; and scientific journal references.
By providing access to this data, Newport Horizon Premium and Newport Vision Premium now allows customers to gauge which patents are involved, what raw materials are needed, the cost and complexity of the process and whether specialised equipment or facilities must be bought or constructed.
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