Healthcare information and services provider Thieme has released Science of Synthesis (SoS) 4.20, the latest release of its reference resource for reliable synthetic methods. The new release includes chapters covering the synthesis of several chalcogen-containing heterocyclic systems and the applications of chiral scandium complexes in asymmetric synthesis. Among others, the latest updates also cover topics such as the synthesis of various organosilicon, organogermanium, organotin, and organophosphorus compounds. SoS now also features selected direct links to chapters that are useful for teaching advanced organic chemistry courses, as well as for students as a resource for assigned coursework.
In “Free Radicals: Fundamentals and Applications in Organic Synthesis,” the two renowned radical chemists based at Sorbonne University in Paris present highlights in the selective generation of organic radicals and their use in organic synthetic reactions in a readily accessible and practical fashion. The latest release of SoS includes Volume 2, which covers a variety of topics such as organic electron donors in electron-transfer reactions, selective radical fluorinations, and radical chemistry inflow, in reviews that are compiled by experts in each area. Volume 1 will be included in the next release of SoS.
Other highlights of this release are updates on the synthesis of α-silyl alcohols, ethers, and amines (Q.-W. Zhang, K. An, and W. He) and allenylsilanes (N. Krause and N. Arisetti), metalated germanium compounds (C. Marschner), germylamines (C. S. Weinert), and silylated germanes and silylated stannanes (J. A. Hlina). The content was also updated with regard to the synthesis of cyclic phosphines (D. Gudat) and phosphates and thiophosphates (B. A. Kashemirov, K. Blazewska, K. Justyna, J. Lyu, and C. E. McKenna).
New chapters cover the synthesis of a range of chalcogen-containing six-membered heterocyclic systems, including pyranones and pyranthiones (F. V. Singh), 2H-1-benzopyran-2-ones and 2H-1-benzopyran-2-thiones (B. Cheng and T. Wang), 1H-2-benzopyran-1-ones, 3H-2-benzopyran-3-ones, 6H-dibenzo[b,d]pyran-6-ones, 9H-xanthen-9-ones, and 9H-xanthene-9-thiones (W.-C. Gao and J. Tian), 3-oxidopyrylium salts and their thio and benzo-fused analogues (B. Jiang and C.-F. Zhu). Furthermore, there is a new chapter on the applications of chiral scandium complexes in asymmetric synthesis (W. Li, X. H. Liu, and X. M. Feng).
To support the preparation and teaching of advanced organic chemistry courses, the SoS editorial team has collected some direct links to SoS chapters that can be used as a reference resource when preparing course material. They also serve as an excellent starting point for students for further reading around a topic. Furthermore, SoS now supports Shibboleth/OpenAthens to allow easier access to SoS outside an institution’s network.
