Future Medicinal Chemistry, a journal published by Future Science Ltd., UK, has published a special focus issue dedicated to boron chemistry, with contributions from academic experts based in Europe, North America and Asia. This special focus issue is guest edited by PV Ramachandran (Purdue University), a Herbert Brown Professor and a leading expert in organoborane research.
The special focus issue is dedicated to the discussion of boron-containing molecules that can aid or act as stand alone therapies in the treatment of diseases. Particular attention has been given to boron neutron capture therapy (BNCT), an area of active research for boron chemists for several decades. The issue also provides a forward-looking overview of current efforts, new insights and significant advances in the evaluation and future outlook on this emerging area of medicinal chemistry.
With a selection of absorbing articles including Reviews, Editorials and Preliminary Communications, this issue discusses bio-conjugates for imaging and therapy, boron-containing drug-delivery vehicles, as well as BNCT. In addition, an interview with Fred Hawthorne, one of the pioneers in BNCT research, provides a detailed insight to his research to date. Other additions include the use of antibacterial glycopeptide antibiotics conjugated with benzoxaboroles by Maria Preobrazhenskaya et al. (Gause Institute of New Antibiotics. B.), while an Editorial by Steve Westcott discusses the use of boron-containing capsaicin derivatives for the treatment of cancer.
