Symyx Technologies, Inc., a US-based provider of technologies for R&D, has announced joint releases of the Symyx Direct 6.1 chemistry data cartridge and ISIS/Host 5.2 informatics system for registering, retrieving, displaying and analysing scientific information. These software upgrades - coupled with the upcoming release of Symyx Isentris 3.1 informatics system - are seen to remove a significant ISIS-to-Isentris transition barrier for R&D organisations working with legacy ISIS molecule databases. Symyx Direct 6.1 also enables ISIS customers to take advantage of advances in Symyx chemical representation, stereochemistry and chemical fastsearch capabilities.
Earlier this year at the Symyx Software Symposium in Boston, a major US pharmaceutical company had stated that the Symyx Direct data cartridge surpassed competing cartridges in query speed, accuracy and other test criteria. The chemical cartridge evaluation was undertaken with a view to selecting cartridge technology that would provide the most rapid and advanced substructure searching to increase researcher satisfaction and improve R&D productivity.
According to the company, Symyx Direct is already used by more than 80 percent of life sciences organisations. It is projected to enable researchers to register, search and retrieve molecular structures and reactions stored in Oracle relational databases. The tool supports Data Rgroup, Data Sgroup, flexmatch, 2-D and 3-D exact and molecule/reaction substructure searching; structure similarity, super-similarity and sub-similarity searching; reaction similarity searching; comprehensive structure registration; and searching of tetrahedral stereoisomers and non-tetrahedral stereoisomers using the Symyx NEMA algorithm.
Symyx Direct is claimed to be the only chemistry search engine that combines full reaction transformation searching, chemistry sophistication and proven performance with databases containing over five million reactions and over 27 million structures.
