Information management systems provider Symyx Technologies, Inc., US, has released the Symyx Direct 7.0 data cartridge, an innovative, one-stop solution for registering, searching, and retrieving chemical and biological entities stored in relational databases. Symyx Direct 7.0 will seek to improve R&D efficiency, project team collaboration, and IP management by enabling multidisciplinary project teams to visualise, explore and compare novel macromolecular sequences and chemical structures stored in a single, fully searchable corporate registry system.
Many scientists today are searching for ways to reduce off-target effects and improve the stability of chemically modified short interfering RNA (siRNA) sequences, peptides, and other large molecules. Aiding these efforts, Symyx Direct 7.0 supports natural post- translational modifications (PTM) and custom modifications while also providing seamless support for D-amino acids and complex cyclisations, including the imidasolinone fluorophore found in the fluorescent proteins.
Symyx Direct 7.0 offers a new, hybrid representation that combines the best features of bioinformatics and cheminformatics notations, improving multidisciplinary collaborative research by enabling scientists to register and retrieve molecules, reactions, and biomolecular sequences including peptides, oligonucleotides, and oligosaccharides; search for and view chemical modifications in sequences; and develop structure-activity correlations in sequences. Used by more than 80 percent of life sciences organisations worldwide, the Symyx Direct data cartridge offers proven performance with databases containing more than 30 million structures and more than 17 million reactions.
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