Science of Synthesis 4.22, the latest release of Thieme’s reference resource for reliable synthetic methods, includes the addition of one new update volume comprising approximately 450 printed pages with highlights such as a series of new chapters on the synthesis of pyrido[1,2-a]indoles and azapyrido[1,2-a]indoles. Additionally, the release provides improved access to the teaching resources.
Highlights of this release are a series of new chapters on the synthesis of pyrido[1,2-a]indoles and azapyrido[1,2-a]indoles (P. A. Harris), which occur in a number of biologically active indole alkaloids. A new chapter addresses 1,4-dioxanes (B. V. Vashchenko and O. O. Grygorenko), which are useful scaffolds in organic synthesis and drug design.
The content was also updated with regard to chemoselective ligation methods based on the concept of native chemical ligation (L. R. Malins and R. J. Payne), a modern approach for peptide synthesis. Furthermore, there is a new chapter on biocatalytic oxidation of alcohols (F. Hollmann), highlighting applications in the synthesis of carbonyl and carboxyl compounds.
The Teaching Resources page of SOS now has its own tab, making it easier to access key articles useful for teaching and learning.
Thieme Chemistry is currently offering free access to publications about asymmetric organocatalysis from Nobel Laureate Prof. Ben List: www.thieme-chemistry.com/nobel
