Thieme Chemistry, Germany, has announced the release of Science of Synthesis 4.0.1 - the only full-text resource for methods and experimental procedures in synthetic organic chemistry. The new version, available as of October 6th, 2014, offers a range of new features as well as 13 new content volumes covering topics such as Cross Coupling and Heck-Type Reactions and Multicomponent Reactions. New features include improved text-search capabilities and a new non-Java chemical structure editor.
Eight of the thirteen new volumes on SOS are Science of Synthesis Knowledge Update volumes dating from 2012 to 2014. Highlights include a comprehensive review of asymmetric transformations catalysed by gold salts published between 2005 and 2011 by M. J. Campbell and F. D. Toste; a new chapter outlining many of the methods used to synthesize α-aryl ketones and α-hetaryl ketones by J. C. Collings; and an entirely new chapter on thioaldehyde and thioketone S-sulfides (thiosulfines) overviewing methods for their in situ generation as well as their application by G. Mlostoń and H. Heimgartner.
The other five volumes comprise part of the much-acclaimed Science of Synthesis Reference Library series. Cross Coupling and Heck-Type Reactions consists of three volumes written by 96 experts and edited by G. A. Molander, J. P. Wolfe and M. Larhed. It includes the best methods currently available for the formation of new carbon - heteroatom and carbon- carbon bonds using metal-catalysed cross-coupling reactions. The two volumes Multicomponent Reactions written by 63 leading chemists in the multicomponent reactions field and edited by T. J. J. Müller critically review the state of the art of domino, sequential, and consecutive multicomponent reactions.
With the new HTML5 structure editor, which is very easy and intuitive to use, users can draw chemical structures within their Web browser without the need for plugins like Java. This then eliminates the need to adjust security settings or gain additional administration rights for Java issues as has been the case in the past.
An improved search function enables users to find specific Science of Synthesis articles quickly using additional operators in the text search box.
Science of Synthesis provides a critical review of the synthetic methodology developed to date in the fields of organic and organometallic chemistry. The content is compiled and updated by a community of over 1,750 renowned chemists worldwide.
To get access to the product or a free trial, interested parties may visit - http://sos.thieme.com.
