Bioinformatics software solutions provider Ariadne, US, has announced a joint collaboration with Cellecta and Roswell Park Cancer Institute to develop a comprehensive knowledgebase of prostate-specific pathway models. The project, partially sponsored by an NCI SBIR Phase 1 grant, uses Cellecta's siRNA library screening system for a panel of prostate cancer cell lines to identify genes essential for viability of cancer cells.
Ariadne will use the data from the siRNA screens and available OMICS data to identify pathways involved and build mechanistic models in support of the genes identified from the siRNA targets in the screen. Roswell Park contributes its expertise in prostate cancer biology and clinical applications.
Ariadne helps pharmaceutical and life science researchers tap known scientific knowledge for applications in systems biology and translational medicine. The company provides a portfolio of solutions for life science, drug discovery and development applications including custom data products, knowledge extraction and visualisation software, knowledge reports, and informatics staffing.
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